I don't see how that would help in computing. It would help with compiling sure, but unless you reinvent the transistor, you are still dealing with binary. I would actually love to see an example on how it would be set up. I have a few ideas, but none that would be practical.

the impracticality here comes in diferentiating each of the 16 values of charge. differentiating 2 values across a spectrum going from zero to one is a hell of a lot easier than meassuring 16 values between zero and one. if you increase the voltage, you end up with more signal noise, and have higher risk of delicate circuitry failing on you. back around the end of the 90's/early 2000's, there were some, i think sony was one of them, who tried a system with three states, 0, 1, and 2. it failed and i assume there is a reason it isn't brought back.
a hexadecimal system is not happening this century.

A few teachers and students at my college were trying to last year. Its possible this century.

I mean Laci