its more than that. the guy getting his ass whooped is supposed to be the pinnacle of esper science because he counters whatever you throw at him. however the guy punching him in the face cancels everything not normal using an unscientific power. thats why its hilarious.
And to make it even more hilarious, the power negating ability is only limited to his right hand. So he's extremely vulnerable but he still kicks Accelerator's ass because he caught him completely off guard.
Scenario #1: It cancels Saitama's ridiculous strength completely and nobody dies.
Scenario #2: Saitama's strength is result of rigorous training and is not supernatural ability, Touma gets splattered across the street and building at the end of said street.
i said brofist not hardpunch.
i doubt they would try to hurt each other. the way they are is very similar.
but saitamas power is supernatural. it reaches beyond physics.