Interestingly enough, even though the Lone Wanderer was only in a Vault jumpsuit, it looked like the Dragonborn was wearing Iron armor, so in terms of protection they look to be a pretty even match.
The Dragonborn's sword, most likely iron, isn't very impressive but his Destruction spells and, obviously, shouts made up for it. This puts him on par with the Lone Wanderer's weapons, although the Laser RCW seemed to be a tad overpowered.
That being said, Odahviing definitely was a trump card.
It would have been interesting to see how this would play out with max-level characters - the Dragonborn wielding mostly Daedric/Glass, Dragonbone/scale, or Stahlrim gear, and the Lone Wanderer in T-51b, T-45d or Enclave power armor.
and i dare say i like both games and dont care for fanbase bull crap over who will win but in terms of lore dovakiins just over powered and would have won.
the lone wanderer is just a normal human with guns the dovakiin has magic shouts and sword.
realistically shouts dont have a cool down but ingame its made that way to be balanced. dovakiin should have shouts like become ethereal or slow time.
its an amazing video epic infact i can only imagine how much work was put into it.